The National Institute on Deafness and Other Communication Disorders (NIDCD) invites applications for Clinical Research Center Grants designed to advance the diagnosis, prevention, treatment, and amelioration of human sensory and communication disorders.
Donor Name: National Institute on Deafness and Other Communication Disorders (NIDCD)
State: All States
County: All Counties
Type of Grant: Grant
Deadline: 10/04/2025
Size of the Grant: More than $1 million
Grant Duration: 5 Years
Details:
The P50 Clinical Research Center provides a vehicle for integrated, multidisciplinary approaches to critical clinical research questions that advance the study of prevention, pathogenesis, pathophysiology, diagnosis, treatment, management or epidemiology of a disease or disorder of hearing, balance, smell, taste, voice, speech, or language. The P50 provides an avenue for forming a multi-disciplinary team that is intended to bring innovative ideas and distinct perspectives to the generation and evaluation of high impact solutions to complex clinical problems. Responsive applications must include a multi-disciplinary team collaborating on a synergistic set of 3-4 research projects addressing a unifying theme. The synergistic and substantial integration of research projects is intended to generate breakthrough solutions to the unifying problem. The research efforts are further supported by an administrative core and 1-2 optional scientific cores to ensure rigorous and efficient progress towards the center’s unifying theme. Overall, the clinical research center provides a whole that will have impact beyond the sum of its parts.
Required Elements
To be responsive to this funding opportunity, a Clinical Research Center must include the following required conceptual and structural elements
- Clinical Research
- For this funding opportunity, the research being conducted must have a clinical focus, usually defined as research involving individuals with sensory and/or communication disorders or data/tissues from individuals with a sensory and/or communication disorder.
- Multidisciplinary
- The overall P50 must provide multidisciplinary approaches to the central theme, defined as having research projects representing different disciplines, approaches and expertise.
- External Advisory Committee
- Each proposed Center must have an external advisory committee. The external advisory committee will provide oversight of scientific progress of the Center and guide the research plan when appropriate. Members of the external advisory committee should not be named in new applications.
Non-Responsive Applications
The following applications will be considered non-responsive for this funding opportunity and will not be reviewed:
- Applications outside NIDCD mission areas
- Applications where the majority of the research does not focus on individuals with sensory and/or communication disorders and/or data/tissue from individuals with sensory and/or communication disorders
- Applications that include clinical trials entailing greater than low-risk
- Applications that do not have synergistic and substantial interaction around a unifying theme
- Applications that are not multidisciplinary
- Applications that have a scientific core or cores used by only one research project
- Applications that do not describe an external advisory committee in terms of general expertise and planned activities
Funding Information
Budgets for new applications are limited to $1,500,000/per year direct costs, exclusive of consortium facilities and administrative costs. Renewal (type 2) grant applications may request direct cost budgets that are not greater than 10% above the budget of the last year of the existing award or $2,000,000 whichever is less; this is also exclusive of consortium facilities and administrative costs.
Project Period
The maximum project period is 5 years.
Eligibility Criteria
Higher Education Institutions – Includes all types
- Public/State Controlled Institutions of Higher Education
- Private Institutions of Higher Education
Nonprofits Other Than Institutions of Higher Education
- Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
For-Profit Organizations
- Small Businesses
- For-Profit Organizations (Other than Small Businesses)
Local Governments
- State Governments
- County Governments
- City or Township Governments
- Special District Governments
- Indian/Native American Tribal Governments (Federally Recognized)
- Indian/Native American Tribal Governments (Other than Federally Recognized)
Federal Governments
- Eligible Agencies of the Federal Government
- U.S. Territory or Possession
Other
- Independent School Districts
- Public Housing Authorities/Indian Housing Authorities
- Native American Tribal Organizations (other than Federally recognized tribal governments)
- Faith-based or Community-based Organizations
- Regional Organizations
Foreign Organizations
- Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.
- Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.
- Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
For more information, visit Grants.gov.