The National Institutes of Health (NIH) invites applications to examine the efficacy of digital health technology approaches to the management of diabetes.
Donor Name: National Institutes of Health (NIH)
State: All States
County: All Counties
Territory: Puerto Rico, Guam, U.S. Virgin Islands, American Samoa, and the Northern Mariana Islands
Type of Grant: Grant
Deadline: 10/07/2025
Size of the Grant: More than $1 million
Grant Duration: 5 Years
Details:
To promote extramural biomedical research that improves the understanding of disease management and leads to improved preventions, diagnosis, and treatment of diabetes, digestive, and kidney diseases. Programmatic areas within the National Institute of Diabetes and Digestive and Kidney Diseases include diabetes, digestive, endocrine, hematologic, liver, metabolic, nephrologic, nutrition, obesity, and urologic diseases.
For this NOFO, DHT includes but is not limited to continuous glucose monitoring (CGM), telemedicine with virtual coaching, connected digital devices (e.g., smartwatches, activity monitors, digital scales), mobile health (mHealth) applications for monitoring clinically relevant parameters such dietary intake, medication adherence, mood, behavior, and methods to facilitate bidirectional information exchange with the health care team, including directed text messaging and patient portals. The application of digital interventions utilizing peer support mechanisms to improve diabetes care also are applicable to this NOFO.
Special areas of research interest
General principles
- Multimodality DHT interventions that for example, combine CGM concurrently with other digital interventions in a virtual remote continuous care intervention, though not required, are of particular interest to this NOFO.
- All investigators are expected to include meaningful engagement approaches with the relevant research population in designing and implementing the proposed trial. This may involve engagement with patients, family members or caregivers, community members, community-based organization, clinicians and other care providers, health care systems, or other relevant partners throughout the research process. Meaningful engagement must entail more than focus groups, surveys, or other activities where partners are only involved as participants or respondents. Engagement must be designed to ensure that the research is practical and aligns with partners’ preferences and values. Meaningful collaboration will lead to optimal trial recruitment and conduct as well as potential for future dissemination and sustainability.
- Multiple digital interventions have applicability to management of both T1 and T2 diabetes and these DHT interventions are of interest to this NOFO.
- Partnering with industry providers of virtual diabetes clinic offerings is allowed but not required.
- Clinical trials funded in response to this NOFO are expected to provide efficacy data that will enable future large multicenter clinical effectiveness studies on the application of DHT to PWD.
Funding Information
Direct costs and funds available will be 1.5M in 2026, 3.0M in FYs 2027-2030, and 1.5M in FY2031.
Project Period
The maximal project period is 5 years.
Eligibility Criteria
Higher Education Institutions – Includes all types
- Public/State Controlled Institutions of Higher Education
- Private Institutions of Higher Education
Nonprofits Other Than Institutions of Higher Education
- Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
For-Profit Organizations
- Small Businesses
- For-Profit Organizations (Other than Small Businesses)
Local Governments
- State Governments
- County Governments
- City or Township Governments
- Special District Governments
- Indian/Native American Tribal Governments (Federally Recognized)
- Indian/Native American Tribal Governments (Other than Federally Recognized).
Federal Governments
- Eligible Agencies of the Federal Government
- U.S. Territory or Possession
Other
- Independent School Districts
- Public Housing Authorities/Indian Housing Authorities
- Native American Tribal Organizations (other than Federally recognized tribal governments)
- Faith-based or Community-based Organizations
- Regional Organizations
Foreign Organizations
- Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.
- Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.
- Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
For more information, visit Grants.gov.
