The National Institutes of Health (NIH) is seeking applications to support analyses of existing RADx-UP data by proposing novel questions related to SARS-CoV-2 testing and health disparities.
Donor Name: National Institutes of Health (NIH)
State: All States
County: All Counties
U.S. Territories: American Samoa, Commonwealth of Northern Mariana Islands, Commonwealth of Puerto Rico, Guam, U.S. Virgin Islands
Type of Grant: Grant
Deadline: 06/02/2023
Size of the Grant: $275,000
Grant Duration: 2 years
Details:
These projects will explore important questions focused on COVID-19 testing access and uptake, factors affecting testing and related COVID-19 outcomes, and meta-analyses of specific COVID-19 response and intervention approaches within and across populations.
The RADx®-UP initiative seeks to address COVID-19 morbidity and mortality disparities among underserved and vulnerable populations with disproportionate rates of SARS-CoV-2 and/or undue COVID-19 burden by understanding strategies and interventions to increase testing access, acceptability, and uptake. To date, more than 135 projects are engaging participants in all US states as well as American Samoa, the District of Columbia, Guam, the Northern Mariana Islands, Puerto Rico, and the US Virgin Islands.
Goals
- The Office of the Director (OD) is requesting applications for grants (R21) addressing the objectives described below. Projects supported via this Notice of Funding Opportunity will be part of the RADx®-UP initiative. This “Novel Insights through Cross-Site Analyses of Existing RADx-UP Data” opportunity will support new exploratory/developmental grants for analysis of existing data collected within the RADx-UP consortium. Successful applications will leverage common demographics and other data from a minimum of three sites (with geographic diversity; inclusion of a greater number of sites is encouraged) to ask important questions around COVID-19 testing access and uptake. Applications that address factors affecting COVID-19 testing and related COVID-19 outcomes, specific COVID-19 response, intervention approaches within and across populations, and other novel questions are encouraged.
- To maximize the scientific potential of valuable RADx-UP data and resources, analyses of existing archived data will allow applicants to further develop and build upon original research. Analyses of existing datasets offers a cost-effective way to collaborate and foster research within NIH’s scientific mission. The application of rigorous and new analysis methodologies that merge or link various RADx-UP datasets and de-identified variables is encouraged. Generation of metadata will allow researchers the opportunity to increase statistical power and accuracy in estimates across studies, going beyond original hypotheses to answer new research questions.
Research Objectives:
This research seeks to gain novel insights regarding data collected by RADx-UP studies that have shared both common and project-defined data elements on multiple topics related to COVID-19 testing and disparities among underserved and vulnerable groups.
All applications utilizing existing RADx-UP datasets and collections to explore new research questions relevant to the mission of RADx-UP will be considered. Generation of new primary data is not allowed. This Notice of Funding Opportunity will not support the collection of new data.
The data analyses will be focused on underserved and vulnerable populations and questions related to reducing health disparities based on topics and research studies that include, but are not limited to, the following areas:
- Testing Interventions: Analyses to evaluate the effectiveness of testing interventions and/or what testing interventions can be implemented to decrease COVID-19 disparities in different regions of the U.S. and across demographic groups.
- COVID-19 Testing Options: Analyses to determine what COVID-19 testing options (e.g., surveillance, symptomatic, etc.) are most acceptable and in what setting (such as community-based organizations, health clinics, school/academic environments).
- Common Data Elements: Analyses of Common Data Elements for novel data comparison and synthesis across project sites and smaller population groups.
- Social Determinants of Health (SDOH): Analyses on how SDOH help identify, understand, and address testing and vaccine access and uptake in low-resourced geographic areas or communities with high levels of social vulnerability.
- Community-Engaged Interventions to address Stigma, Bias, Distrust and Fear: Analyses on what type of community-driven interventions effectively ameliorate stigma, bias, distrust, and fear regarding symptomatic and asymptomatic COVID-19 testing and vaccination.
- Psychosocial, Behavioral, and Ethical Factors Driving COVID-19 Testing and Vaccination: Analyses on what specific psychosocial, behavioral, and ethical factors drive COVID-19 testing and vaccine uptake within and across underserved populations, including the role of healthcare, academic, and social service settings in response to COVID-19 health disparities.
- Messaging and Policies Impact on COVID-19 Testing and Vaccination: Analyses on whether and how messaging and policies at the local, state, and federal levels in different jurisdictions affect COVID-19 testing and vaccine uptake over time.
Funding Information
Application budgets are limited to a total of $275,000 direct costs over the two-year project period.
Award Project Period
The maximum project period is two years.
Eligibility Criteria
Higher Education Institutions
- Public/State Controlled Institutions of Higher Education
- Private Institutions of Higher Education
The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:
- Hispanic-serving Institutions
- Historically Black Colleges and Universities (HBCUs)
- Tribally Controlled Colleges and Universities (TCCUs)
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
Nonprofits Other Than Institutions of Higher Education
- Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
For-Profit Organizations
- Small Businesses
- For-Profit Organizations (Other than Small Businesses)
Local Governments
- State Governments
- County Governments
- City or Township Governments
- Special District Governments
- Indian/Native American Tribal Governments (Federally Recognized)
- Indian/Native American Tribal Governments (Other than Federally Recognized)
Federal Government
- Eligible Agencies of the Federal Government
- U.S. Territory or Possession
Other
- Independent School Districts
- Public Housing Authorities/Indian Housing Authorities
- Native American Tribal Organizations (other than Federally recognized tribal governments)
- Faith-based or Community-based Organizations
- Regional Organizations
Foreign Institutions
- Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.
- Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.
- Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
For more information, visit Grants.gov.
