National Institutes of Health is seeking applications to enable early-stage research to better understand the underlying causes of radiation-associated sex differences to advance radiation preclinical animal models, improve MCM development, increase the safety and efficacy of MCMs, and advance biomarker science to assess radiation injuries.
Donor Name: National Institutes of Health
State: All States
County: All Counties
Territory: Puerto Rico, U.S. Virgin Islands, American Samoa, Northern Mariana Islands, and Guam
Type of Grant: Grant
Deadline: 09/06/2023
Size of the Grant: $350,000
Grant Duration: 3 years
Details:
Purpose
The National Institute of Allergy and Infectious Diseases (NIAID) Division of Allergy, Immunology, and Transplantation’s (DAIT) Radiation and Nuclear Countermeasures Program (RNCP) has been tasked with developing safe and effective medical countermeasures (MCMs) and biodosimetry tools for civilians, which can be used 24 hours or later post-exposure during a radiological or nuclear public health emergency. This Notice of Funding Opportunity (NOFO) is intended to elucidate sex-dependent effects that occur after radiation exposure. Historically, radiation studies predominantly utilized male animals, leading to an insufficient sex balance in preclinical study data that were not representative of the general population. Although this practice has changed over time and the inclusion of female animals has increased, the available radiation data powered for sex-dependent variables are still limited. While many studies demonstrate sex trends, they lack statistical power for definitive results and conclusions. This NOFO seeks to ensure studies are well-powered to include both female and male data to better understand underlying sex-related differences to advance radiation preclinical animal models, improve MCM development, increase the safety and efficacy of MCMs, and advance biomarker science to assess radiation injuries.
Funding Information
Application budgets are not expected to exceed $350,000 in direct costs per year and should reflect the actual needs of the proposed project.
Award Project Period
The scope of the proposed project should determine the project period. The maximum project period is 3 years.
Eligibility Criteria
- Higher Education Institutions
- Public/State Controlled Institutions of Higher Education
- Private Institutions of Higher Education
- The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:
- Nonprofits Other Than Institutions of Higher Education
- Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- For-Profit Organizations
- Small Businesses
- For-Profit Organizations (Other than Small Businesses)
- Local Governments
- State Governments
- County Governments
- City or Township Governments
- Special District Governments
- Indian/Native American Tribal Governments (Federally Recognized)
- Indian/Native American Tribal Governments (Other than Federally Recognized)
- Federal Government
- Eligible Agencies of the Federal Government
- U.S. Territory or Possession
- Other
- Independent School Districts
- Public Housing Authorities/Indian Housing Authorities
- Native American Tribal Organizations (other than Federally recognized tribal governments)
- Faith-based or Community-based Organizations
- Regional Organizations.
For more information, visit Grants.gov.
