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HEAL Initiative: Translating Research to Practice to End the Overdose Crisis 

The National Institutes of Health is accepting applications for Translating Research to Practice to End the Overdose Crisis.

Donor Name: National Institutes of Health

State: All States

County: All Counties

Territory: Commonwealth of Puerto Rico, U.S. Virgin Islands, Guam, American Samoa, Commonwealth of the Northern Mariana Islands

Type of Grant: Grant

Deadline: 03/20/2024

Size of the Grant: $750,000

Grant Duration: 6 years

Details:

Purpose

The goal of this FOA is to support action-oriented research that accelerates the translation of research to practice to address the overdose crisis. There remains an urgent need for research to address understudied areas of opportunity, particularly addressing the fundamental barriers or facilitators to reducing overdose deaths at the individual, provider, organizational, community, or system levels.  High priority areas are those that advance the goal of creating stigma-free patient-centered systems of care such that people who experience addiction can recover and sustain their recovery over the long-term.

Applications should attend to methods to accelerate the translation of insights generated by the proposed research into practice. Methods such as implementation science, hybrid implementation/effectiveness trials, and dissemination research are critical tools for achieving this acceleration. Applications must be innovative and should not focus on replicating previous findings. Key elements that must be considered in all applications include:

  • Meaningful engagement of relevant practitioners and community stakeholders in study conceptualization, design, execution, and interpretation;
  • Potential scalability of the proposed intervention, including perspectives of prospective payers should the proposed intervention prove to be successful;
  • Sustainability of the proposed intervention should it prove to be successful;
  • Health disparities and inequities and the relevance to the interventions or services being studied;
  • Perspectives of patients or recipients of the services or interventions being studied.

In addition to areas of interest specified by such NOSIs, effectiveness, services, or implementation questions relevant to treatment of opioid use or stimulant use disorder, harm reduction, and recovery support are of general interest. Examples of specific areas of interest include, but are not limited to:

  • Provider, organizational, community, or system-level interventions that seek to enhance uptake of evidence based practices;
  • Studies that test novel and efficient service delivery models for OUD and other comorbid medical and mental conditions;
  • Studies that seek to identify, develop, test, evaluate, and/or refine strategies to disseminate and implement evidence-based practices (e.g. behavioral interventions; prevention, early detection, diagnostic, treatment and disease management interventions; quality improvement programs) into public health, clinical practice, and community (e.g., workplace, school, place of worship) settings to address opioid or stimulant use and comorbid medical and mental conditions, including pain;
  • Approaches that enhance the quality, effectiveness, affordability, or utilization of existing treatments for opioid use disorder (OUD) and comorbid medical or mental conditions, including pain;
  • Studies that address novel research questions that would otherwise not be addressed by programs or infrastructure supported through other funders (e.g., Substance Abuse and Mental Health Services Administration (SAMHSA), Health Resources & Services Administration (HRSA), Bureau of Justice Assistance (BJA), settlement funds, private funders, etc.);
  • Studies that seek to understand major changes or variations in the service delivery environment that may facilitate or impede the delivery of effective, high-quality, patient-centered services;
  • Projects that seek to understand circumstances and test strategies to stop or reduce (i.e., “de-implement”) the use of interventions that are ineffective, unproven, low-value, or harmful in efforts to demonstrably free up resources and then implement a high-value evidence-based practice
  • Strategies that seek to improve quality, timeliness, and utility of data to inform and support real-time proactive responses within systems and in cross-system collaborations;
  • Multi-level intervention designs that tackle multiple barriers to or facilitators of access to evidence-based services.

Funding Information

  • Unless well-justified, it is strongly recommended that applicants not request a budget of more than $300,000 in direct costs per year for the R61 phase and $750,000 in direct costs per year for the R33 phase of the project.
  • The maximum period of the combined R61 and R33 phases is 6 years, with a maximum of 2 years for the R61 phase and maximum of 5 years for the R33 phase of the project.

Eligibility Criteria

  • Higher Education Institutions
    • Public/State Controlled Institutions of Higher Education
    • Private Institutions of Higher Education
  • The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:
    • Hispanic-serving Institutions
    • Historically Black Colleges and Universities (HBCUs)
    • Tribally Controlled Colleges and Universities (TCCUs)
    • Alaska Native and Native Hawaiian Serving Institutions
    • Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
  • Nonprofits Other Than Institutions of Higher Education
    • Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
    • Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
  • For-Profit Organizations
  • Local Governments
    • State Governments
    • County Governments
    • City or Township Governments
    • Special District Governments
    • Indian/Native American Tribal Governments (Federally Recognized)
    • Indian/Native American Tribal Governments (Other than Federally Recognized)
  • Federal Government
    • Eligible Agencies of the Federal Government
    • U.S. Territory or Possession
  • Other
    • Independent School Districts
    • Public Housing Authorities/Indian Housing Authorities
    • Native American Tribal Organizations (other than Federally recognized tribal governments)
    • Faith-based or Community-based Organizations
    • Regional Organizations.

For more information, visit Grants.gov.

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