NIH: Understanding Chronic Conditions Understudied Among Women

The National Institutes of Health is seeking applications on chronic conditions understudied among women and/or that disproportionately affect populations of women who are understudied, underrepresented, and underreported in biomedical Research should align with Goal of the Trans-NIH Strategic Plan for Women’s Health Research “Advancing Science for the Health of Women.

Donor Name: National Institutes of Health (NIH)

Deadline: 06/20/2024

Size of the Grant: $350,000

Grant Duration: 4 years

Details:

The awards under this NOFO will be administered by NIH ICs using funds that have been made available through the Office of Research on Women’s Health (ORWH) and the scientific partnering Institutes and Centers across NIH.

This NOFO aligns with Goal 1 of this NIH Strategic Plan, advancing rigorous research that is relevant to the health of women which contains the following objectives:

• Discover basic biological differences between females and males.
• Investigate the influence of sex and gender on disease prevention, presentation, management, and outcomes.
• Identify the immediate, mid-, and long-term effects of exposures on health and disease outcomes.
• Promote research that explores the influence of sex and gender on the connection between the mind and body, and its impact on health and disease.
• Expand research on female-specific conditions and diseases, including reproductive stages, and maternal and gynecologic health.

Specific research areas of interest to NHLBI include, but are not limited to, the following:

• Mechanisms of chronic debilitating diseases/conditions with increased or exclusive HLBS manifestation in women, including those who identify as sexual and/or gender minorities (SGM).
• Consideration of female sex and sex hormones in cellular and animal models of chronic HLBS diseases and disorders.
• The influence or interaction of environmental factors (including psychosocial, socioeconomic, and sociocultural determinants of health) in development, diagnosis, and treatment of chronic HLBS disorders in women.
• AI/ML/modeling approaches to predict development and support treatment of chronic HLBS disorders relevant for women’s health across life span (including pregnancy and postpartum period).
• Understanding chronic debilitating HLBS diseases in women at the molecular level by analyzing whole genome sequence and additional omics datasets such as those found in the NHLBI TOPMed database.
• Studies on models of effective community engagement and health communication that can contribute to increased awareness and dissemination of scientific findings on chronic diseases in women, especially in low income or underserved communities.
• Exploration of the mechanisms that underlie sex- and gender-specific challenges, barriers, and facilitators in the development and implementation of female-specific evidence-based guidelines for chronic HLBS disorders.
• Studies on models of both efficient and effective HLBS healthcare delivery to women across the life course, especially those from underserved populations or communities, and/or that promote HLBS healthcare equity for women from all racial/ethnic/national/cultural/socioeconomic/geographic/sexual/gender backgrounds.
• Research to better understand resilience to chronic debilitating HLBS diseases and multimorbidity in women, including in sexual and gender minority women (e.g., women have high prevalence of, but lower mortality from pulmonary artery hypertension.
• Research related to the prevention or treatment of chronic debilitating HLBS diseases in women, including pilot or full scale efficacy trials.
• Research related to the prevention or treatment of chronic debilitating HLBS diseases in sexual and/or gender minority women, including pilot or full scale efficacy trials.

Funding Information

Application budgets may not exceed direct costs of $350,000 per year.

Project Period

The total project period for an application submitted in response to this NOFO may not exceed 4 years.

Eligible Organizations

Higher Education Institutions

• Public/State Controlled Institutions of Higher Education
• Private Institutions of Higher Education

The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:

• Hispanic-serving Institutions
• Historically Black Colleges and Universities (HBCUs)
• Tribally Controlled Colleges and Universities (TCCUs)
• Alaska Native and Native Hawaiian Serving Institutions
• Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)

Nonprofits Other Than Institutions of Higher Education

• Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
• Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)

For-Profit Organizations

• Small Businesses
• For-Profit Organizations (Other than Small Businesses)

Local Governments

• State Governments
• County Governments
• City or Township Governments
• Special District Governments
• Indian/Native American Tribal Governments (Federally Recognized)
• Indian/Native American Tribal Governments (Other than Federally Recognized)

Federal Government

• Eligible Agencies of the Federal Government
• U.S. Territory or Possession

Other

• Independent School Districts
• Public Housing Authorities/Indian Housing Authorities
• Native American Tribal Organizations (other than Federally recognized tribal governments)
• Faith-based or Community-based Organizations
• Regional Organizations

Foreign Institutions

• Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.
• Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.
• Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

For more information, visit Grants.gov.