Request for Proposals for CREATE U.S. Program 2023

The CREATE U.S. Program is in addition to Gilead’s existing Investigator Sponsored Research Program, which supports investigator-sponsored research conducted by clinicians and researchers on Gilead’s marketed products and/or within therapeutic areas of interest to the company.

Focus Areas

• Through the CREATE U.S. Program, Gilead will evaluate and potentially support proposals which address one of the following topic areas with a particular focus of key affected communities and sub-populations of people with HIV (PWH) facing barriers to access, adherence and/or quality of care:
  • Identifying innovative approaches to re-engage and continually engage people with HIV in HIV care, in particular ensuring rapidly re-starting HIV treatment following a treatment interruption
  • Adapting, pilot testing or evaluating practical evidence-based initiatives, programs or support systems to support PWH
  • Sustain long term virologic suppression
  • Access stigma-free care
  • Obtain person-centered care
  • Enhance quality of life including mental health
• Key affected communities/sub-populations include (but may not be limited to): Black, Indigenous, and/or people of color; transgender women; cisgender women; individuals ≥ 50 years of age; youth; immigrants/migrants; homeless/marginally housed; commercial sex workers; persons who use drugs or other substances; those with mental illness and/or clinical co-morbidities; individuals with viremia, low CD4, and/or pre-existing resistance; and low socioeconomic status/uninsured populations.

Funding Information

• There will be two award tiers as described:
  • Tier A (award up to $200,000)
    • Applicant is a community-based organization with an established track record in conducting and presenting/publishing CBPR
    • Proposed study involves a larger scale or more involved/intensive intervention or the impact of the research program that will affect a wider population
  • Tier B (award up to $50,000)
    • Applicants from all other community-based organizations
    • For community-based organizations who are applying for Tier B and wish to discuss their proposals, Gilead may be able to provide the contact information for a third-party vendor that may offer limited consultations. Topics could include basic research consultations, measuring endpoints, survey development, etc. The request for these vendor services is made at the time of Letter of Intent (LOI) submission. Gilead has not contracted with the vendor for these services, and the community-based organization must independently reach out to the vendor for any consultation.

Eligibility Criteria

• Applicant’s organization must provide services including but not limited to health or social services, education or advocacy for populations most impacted by HIV.
• Applicant’s organization must be based in the United States.
• Proposal should directly address a specific research question.
• Proposal should not include any medications for the treatment of HIV and should not evaluate the safety or efficacy of any medication.

Research Criteria

• Have clear scientific objectives based on scientific hypotheses. For proposals that are descriptive only or fully qualitative in nature, where this may not apply, please explain how results will be used to improve programs or generate hypotheses for future studies
• Collect appropriate metrics using defined, specific, and appropriate data collection methods
• Have a plan to present results in scientific or large community forum and to other organizations, and to publish results in peer-reviewed journals
• Note potential scalability and sustainability of the program once funding is complete (when applicable)
• Highlight generalizability or applicability to other community settings
• The proposed research will not take longer than 12 months to complete
• Proposal should originate from a community entity and be led by a non-academic individual (e.g. one who has neither an academic appointment nor is employed at a higher learning institution). However, community groups as study leads can propose to partner with an academic institution to bolster research capacity.

For more information, visit Gilead.