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Research Networks to Promote Multidisciplinary Mechanistic Studies on Music-Based Interventions

The purpose of this FOA is to support a collection of research networks that promote multidisciplinary mechanistic studies of music-based interventions (MBIs) for pain or Alzheimer’s disease and Alzheimer’s disease-related dementias (AD/ADRD).

Donor Name: National Institutes of Health

State: All States

County: All Counties

Territory: American Samoa, Commonwealth of Puerto Rico, Commonwealth of the Northern Mariana Islands, Guam, and U.S. Virgin Islands

Type of Grant: Grant

Deadline: 01/10/2023

Size of the Grant: $300,000

Grant Duration: 5 years

Details:

These networks are expected to develop compelling research frameworks that will effectively guide future clinical studies on MBIs in these health conditions; adopt consistent terminology and taxonomy; support interdisciplinary collaborations and initiate pilot projects to test novel mechanistic hypotheses; and identify strong mechanistic measures, outcomes, biomarkers, as well as relevant novel technologies and methodologies. To accomplish these objectives, applicants can propose activities such as meetings, workshops, conferences, research collaborations, exchange of ideas through visiting scientist arrangements or training opportunities. These activities will help identify unique research gaps that can be addressed through the networks in the form of pilot projects which will in turn generate the preliminary data needed for music and health investigators to compete for more substantial NIH grants. In addition, the networks should sustain their scientific impact through a variety of dissemination and outreach strategies, including publication of research frameworks, common terminologies, reviews, and other best practices.

Requirements and Scope

This FOA is intended to support the development of research networks designed to promote multidisciplinary mechanistic studies of music-based interventions (MBIs) for pain or AD/ADRD.

  • The scientific scope of the networks is limited to the following high-priority research areas:
    • Research Area One: Music-based Interventions
      • Definition and differentiation of different types of MBIs (e.g., passive listening vs. active engagement, self-management vs. therapist-based)
      • Identification and/or definition of various active components of music  (e.g., melodies, chords, rhythms, musical expression) or MBIs (e.g. social interaction, expectation, attention, movement)
    • Research Area Two: Mechanisms and Biomarkers
      • Exploration of innovative neural mechanistic hypotheses of the systems involved in the therapeutic effect of music (e.g., sensory, motor, cognitive, emotional/affective, reward, interoceptive systems) in pain or AD/ADRD
      • Examination of non-neural physiological systems and novel measures (e.g., impact on related non-neural organs, biochemical and molecular signals, epigenetic modifications, etc.) relevant to music or MBIs for pain or AD/ADRD
      • Discovery of treatment response or predictive biomarkers or signatures/profiles for MBIs in the context of pain or AD/ADRD
    • Research Area Three: Technologies, Tools, & Models
      • Development of novel technologies to measure how MBIs impact various functions of the brain and body, or to monitor health-related responses for pain or AD/ADRD
      • Development and testing of innovative animal models to study mechanisms and biomarkers of MBIs in the context of pain or AD/ADRD.

Funding Information

  • Application budgets are limited to $300,000 in direct costs per year.
  • The maximum project period is 5 years

Eligibility Criteria

  • Higher Education Institutions
    • Public/State Controlled Institutions of Higher Education
    • Private Institutions of Higher Education
  • The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:
    • Hispanic-serving Institutions
    • Historically Black Colleges and Universities (HBCUs)
    • Tribally Controlled Colleges and Universities (TCCUs)
    • Alaska Native and Native Hawaiian Serving Institutions
    • Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
  • Nonprofits Other Than Institutions of Higher Education
    • Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
    • Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
  • For-Profit Organizations
  • Local Governments
    • State Governments
    • County Governments
    • City or Township Governments
    • Special District Governments
    • Indian/Native American Tribal Governments (Federally Recognized)
    • Indian/Native American Tribal Governments (Other than Federally Recognized)
  • Federal Governments
    • Eligible Agencies of the Federal Government
    • U.S. Territory or Possession
  • Other
    • Independent School Districts
    • Public Housing Authorities/Indian Housing Authorities
    • Native American Tribal Organizations (other than Federally recognized tribal governments)
    • Faith-based or Community-based Organizations
    • Regional Organizations.

For more information, visit Grants.gov.

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