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You are here: Home / Grant Size / $500,000 to $1 Million / HEAL Initiative: Research Studies to Develop and Implement Interventions to Prevent Opioid Misuse in Community Health Centers

HEAL Initiative: Research Studies to Develop and Implement Interventions to Prevent Opioid Misuse in Community Health Centers

Dated: July 28, 2022

NIH is issuing this Funding Opportunity Announcement (FOA) in response to the declared public health emergency issued by the Secretary, HHS, for the national opioid crisis. This research is part of the Helping to End Addiction Long-term (HEAL) Prevention Initiative, a portfolio of research focused on the prevention of opioid misuse and opioid use disorder funded under NIHs HEAL Initiative.

Donor Name: National Institutes of Health

State: All States

County: All Counties

Territory: Commonwealth of Puerto Rico, U.S. Virgin Islands, Guam, American Samoa and Commonwealth of the Northern Mariana Islands

Type of Grant: Grant

Deadline: 11/08/2022

Size of the Grant: $750,000

Grant Duration: 5 years

Details:

The National Institute on Drug Abuse (NIDA) seeks to establish the evidence base for interventions that can effectively prevent opioid and other substance misuse in community health centers (CHCs), a setting which serves populations at increased risk for substance misuse.

CHCs are well positioned to serve as a formal point of entry into evidence-based opioid misuse prevention services because they reach a large population impacted by the opioid crisis and are located across the nation in areas with limited health care resources. CHC patients are more likely to experience social and health conditions (e.g., mental disorder diagnosis) that are risk factors for substance misuse and negatively impact their overall health, suggesting prevention may be beneficial for this population. In recent years, CHCs have increased their capacity to provide mental health and substance use treatment services, with 93% of health centers providing mental health treatment and 67% providing substance use treatment services. Despite this capacity, screening for substance use risk (rather than treatment need) and referral to prevention services is uncommon.

This initiative seeks research that will ultimately enhance the capacity of CHCs to screen patients for opioid and substance use risk and refer them to or provide opioid and other substance use prevention services. The two areas of research interest are studies to: (1) develop and test new or adapted interventions to prevent opioid misuse among patients served by community health centers (CHCs), and/or (2) develop and test implementation strategies for screening and referral to preventive interventions for misuse of opioids and other substances among patients served by CHCs.

Examples of priority areas for the two categories of research supported are identified below.

Intervention research

Intervention research applications should be theory based, developing and testing prevention intervention strategies that can be easily integrated into the CHC setting, addressing the unique needs of the community served. Intervention studies may test new interventions or include efficacy and/or effectiveness studies of established interventions that are adapted for CHCs. Intervention studies should test critical components of the prevention strategies for CHC patients to understand the intervention components that impact outcomes. Additionally, the measurement of implementation outcomes and inclusion of economic analyses is encouraged where feasible.

Implementation research

Implementation research applications should inform strategies to increase uptake, effectiveness, and sustainability of screening and referral to prevention among patients served by CHCs.

Funding Information

  • The R61 phase is limited to a budget of no more than $350,000 in direct costs per year. Unless well-justified, it is strongly recommended that applicants not request a budget of more than $750,000 in direct costs per year for the R33 phase.
  • The maximum project period is 5 years. This includes up to 2 years for the R61 phase and up to 4 years for the R33 phase, with the total project period for both phases not to exceed 5 years.

Eligibility Criteria

  • Higher Education Institutions
    • Public/State Controlled Institutions of Higher Education
    • Private Institutions of Higher Education
  • The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:
    • Hispanic-serving Institutions
    • Historically Black Colleges and Universities (HBCUs)
    • Tribally Controlled Colleges and Universities (TCCUs)
    • Alaska Native and Native Hawaiian Serving Institutions
    • Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
  • Nonprofits Other Than Institutions of Higher Education
    • Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
    • Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
  • For-Profit Organizations
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  • Federal Government
    • Eligible Agencies of the Federal Government
    • U.S. Territory or Possession
  • Other
    • Independent School Districts
    • Public Housing Authorities/Indian Housing Authorities
    • Native American Tribal Organizations (other than Federally recognized tribal governments)
    • Faith-based or Community-based Organizations
    • Regional Organizations.

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