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You are here: Home / Grant Size / $500,000 to $1 Million / NIH Centers of Biomedical Research Excellence (COBRE) Program – Phase 3

NIH Centers of Biomedical Research Excellence (COBRE) Program – Phase 3

Dated: July 12, 2023

The National Institutes of Health (NIH) is soliciting applications to transition the core resources and biomedical research activities of Centers of Biomedical Research Excellence (COBRE) into independence and sustainability.

Donor Name: National Institutes of Health (NIH)

State: All States

County: All Counties

Type of Grant: Grant

Deadline: 08/26/2023

Size of the Grant: $750,000

Grant Duration: 5 years

Details: 

The Centers of Biomedical Research Excellence (COBRE) program supports the establishment and development of innovative biomedical research centers to build research capacity at Institutional Development Award (IDeA)-eligible organizations through awards for three sequential five-year phases. The purpose of the COBRE Phase 3 award is to solidify the research base built in Phases 1 and 2 through continued support of research and research infrastructure, and to implement strategies to sustain research excellence beyond COBRE funding.

A COBRE Phase 3 award will provide continued support to solidify successfully established research programs and infrastructure built in prior COBRE phases and to implement strategies to sustain the organization’s research excellence in the Center’s scientific area beyond COBRE funding. All proposed components must be integral to the goals of the Center and are expected to interact with each other and with relevant existing programs at the institution to foster a collaborative research environment.  An established investigator with scientific expertise in the research area of the Center, as well as mentoring and administrative experience, is expected to lead the Center as the Program Director/Principal Investigator (PD/PI) of the award. An Advisory Committee (AC) comprised of institutional leadership and external experts in the research area is required to provide advice on scientific administrative matters critical to the success of the Center.

  • Administrative Core (required)
    • The Administrative Core, to be led by the PD/PI, or the contact PD/PI of a multiple PD/PI application, implements the Center’s overall plan and manages the Center’s operation. It administers a required Pilot Projects Program (PPP) to solidify and expand the Center’s strength in its research area. The PPP is expected to build on the Center’s scientific strengths and encourage the exploration of new ideas, concepts, and approaches. Although independent investigators of all ranks are eligible to lead Pilot Projects, priority should be given to those who qualify as NIH Early Stage Investigators (ESIs) or New Investigators (NIs). Note that Pilot Projects should not be described in the COBRE Phase 3 application and will require post-award approval by NIGMS prior to initiation.
    • The Administrative Core may also assist the PD/PI in recruiting faculty researcher(s) to solidify and/or extend the research expertise of the Center’s current cadre of researchers, especially if one or more of the Research Project Leaders developed through the prior phases of the COBRE awards have left the organization.
    • Other responsibilities of the Administrative Core include:
      • implementing the Center’s plans to sustain research excellence beyond COBRE funding
      • preparing accurate and timely progress reports
      • ensuring all Center activities are compliant with federal regulations
      • managing the Center’s budget and financial reporting
      • organizing Center-wide scientific and career development activities such as seminar series, workshops, and retreats
      • conducting annual performance evaluations of the Center
      • coordinating the activities of the Advisory Committee.

Funding Information

Application budgets must not exceed $750,000 in annual direct costs, excluding consortium facilities and administrative (F&A) costs.

Project Period

The project period is limited to 5 years.

Eligibility Criteria

  • Public and State controlled institutions of higher education
  • Foreign Institutions
    • Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.
    • Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.
    • Foreign components, as defined in the NIH Grants Policy Statement, are not eligible to apply.

For more information, visit Grants.gov.

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