The National Institutes of Health is seeking applications to support a program of longitudinal cohorts to address emerging and high priority research on HIV/AIDS in the context of injection and non-injection substance abuse.
Donor Name: National Institutes of Health
State: All States
County: All Counties
Type of Grant: Grant
Deadline (mm/dd/yyyy): 07/10/2022
Grant Size: $1,000,000
Grant Duration: 5 years
Details:
These cohorts provide a strong resource platform for addressing imminent questions related to HIV prevention, treatment, HIV-associated comorbidities and coinfections in people who use drugs (PWUD).
This FOA aims to support a single coordinating center (CC). The CC is charged with the task of enhancing collaborations and innovation in research to address NIH’s high priority HIV research areas among the cohort investigators and other researchers engaged in the HIV and addiction research field by leveraging the rich data and biospecimen resources available through the cohorts program. The center coordinator(s) will lead the CC and is responsible for the overall performance of the project, including the development, tracking, and reporting of performance metrics by all the currently funded U01 cohort program sites.
Core Areas
The core study areas include:
- Stimulant use and its impact on HIV transmission and clinical outcomes (i.e., viral loads and CD4 cell counts)
- Microbiome and HIV pathogenesis in PWUD
- High risk behaviors associated with drug use and HIV seroconversion
- Immunologic and host genetic factors in HIV seroconversion
- Mathematical modeling and cost-effectiveness studies related to HIV, HCV, and substance use treatment and prevention services
- HIV care models and ART adherence in high risk marginalized populations
- Uptake of HIV testing and prevention services including pre- and post-exposure prophylaxis (PrEP and PEP)
- Long term health consequences of HIV and ART in PWUD
- HIV associated neurocognitive disorder (HAND), aging, cardiovascular and liver disease in people co-infected with HCV
- Social determinants of health disparities related to HIV and SUD, access to care and prevention services for HIV and HIV-related comorbid conditions
- Phylogenetic analysis of HIV clusters in injecting networks
- Molecular studies of HIV infection and persistence in PWUD.
Funding Information
- NIDA intends to commit $1,000,000 in FY23 to fund one award.
- The project period is limited to 5 years.
Eligibility Criteria
- State governments
- Public and State controlled institutions of higher education
- Public housing authorities/Indian housing authorities
- For profit organizations other than small businesses
- Native American tribal governments (Federally recognized)
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- City or township governments
- Native American tribal organizations (other than Federally recognized tribal governments)
- Independent school districts
- County governments
- Special district governments
- Small businesses
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
For more information, visit Grants.gov.
