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You are here: Home / Grant Duration>2 Years / Alternatives in Research Challenge Program

Alternatives in Research Challenge Program

Dated: July 4, 2025

The Alternatives in Research (AiR) Challenge program is an initiative of the Alternatives Research & Development Foundation (ARDF) to support innovative biomedical research that advances human health using non-animal research methods.

Donor Name: Alternatives Research & Development Foundation

State: All States

County: All Counties

Type of Grant: Awards and Prizes

Deadline: 09/15/2025

Size of the Grant: $100,000 to $500,000

Grant Duration: 2 Years

Details:

The goal of the Focus on Childhood Cancer program is to support research that improves the understanding or treatment of childhood cancers while demonstrating the value of non-animal approaches for biomedical progress.

Areas of Interest

  • Projects should be clearly and specifically focused on childhood cancer—either the most common types of cancer that affect children or rarer types. Proposals that address cancer broadly but do not focus on childhood cancers specifically will not be considered responsive.
  • Projects should explicitly address the dual aims of the program’s goal to improve knowledge or treatment of childhood cancers and demonstrate the value of non-animal approaches for biomedical research.
  • Non-clinical or pre-clinical research projects focused on developing non-animal methods/models, novel applications of existing non-animal methods/models, or validation efforts that substantially increase the confidence in existing non-animal methods/models.

Funding Information

Maximum Award per Project: $210,000.

Grant Period

The preferred project period is October 1, 2026 to September 30, 2028.

Eligibility Criteria 

  • Only non-profit, tax-exempt (510(c)(3)), non-governmental, educational and/or research institutions based in the US are eligible to receive AiR Challenge funds.
  • Applicants must have a PhD or MD (or equivalent degree) at the time of LOI submission.

For more information, visit ARDF.

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