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You are here: Home / Grant Duration>5 Years / Cancer Center Support Grants for NCI-designated Cancer Centers

Cancer Center Support Grants for NCI-designated Cancer Centers

Dated: November 27, 2025

The National Institutes of Health (NIH) invites applications for P30 Cancer Center Support Grants (CCSGs) to support NCI-Designated Cancer Centers.

Donor Name: National Institutes of Health (NIH)

State: All States

County: All Counties

Type of Grant: Grant

Deadline: 12/01/2025

Size of the Grant: More than $1 million

Grant Duration: 5 Years

Details:

The purpose of all types of NCI-Designated Cancer Centers is to capitalize on all institutional cancer research capabilities, integrating meritorious research into a single transdisciplinary research enterprise across all institutional boundaries. Cancer Centers supported through this NOFO are expected to serve as major sources of discovery of the nature of cancer and of development of more effective approaches to prevention, diagnosis, and therapy; to contribute significantly to the development of Shared Resources that support research; to collaborate and coordinate their research efforts with other NCI-funded programs and investigators; and to disseminate research findings for the benefit of the community.

The goal of this NOFO is to provide an organizational focus and stimulus for the highest quality cancer research that effectively promotes interdisciplinary cancer research aimed toward the ultimate goal of reducing cancer incidence, mortality and morbidity. The Cancer Center Support Grant (CCSG) provides the resources and infrastructure to facilitate the coordination of interdisciplinary programs across a broad spectrum of research from basic laboratory research to clinical investigation to population science. The CCSG supports salaries for scientific leadership of the Center, shared resources for funded center investigators, certain administrative costs, planning and evaluation, and developmental funds for new recruitments and feasibility studies.

The objectives of the NCI Cancer Centers Program are to foster highly interactive cancer research through support of the following:

  • Formal, interactive scientific Research Programs comprised of investigators with common scientific interests and goals, yielding competitively funded research grants and contracts and productive collaborations;
  • Centralized Shared Resources that provide access to technologies, services, and scientific consultation that enhance scientific interaction and productivity;
  • Strategic planning and evaluation that further the research agenda of the Center;
  • Developmental Funding that allows the Center to pursue newly identified priorities, strengthen weaker scientific areas, and explore new collaborations;
  • Activities that engage the populations within the catchment area in the conducted research and other Center activities;
  • Efforts to coordinate and enhance existing cancer research education, training, and career development activities;
  • Centralized Cancer Center Administration for resources and services, fiscal management and other supportive activities; and
  • Centralized scientific oversight of cancer clinical trials.

CCSGs support three types of Cancer Centers:

  • Comprehensive Cancer Centers, which demonstrate reasonable depth and breadth of research activities in each of three major areas: basic laboratory; clinical; and prevention, control and population-based research, and which have substantial transdisciplinary research that bridges these scientific areas;
  • Clinical Cancer Centers, which are primarily focused on basic laboratory; clinical; and prevention, cancer control, and population-based research; or some combination of these areas; and 
  • Basic Cancer Centers, which focus on basic laboratory research. 

The Six Essential Characteristics of an NCI-Designated Cancer Center

A successful NCI-Designated Cancer Center demonstrates strength in six essential characteristics. Together, these characteristics maximize its scientific potential and produce a whole that is greater than the sum of its parts:

  • Physical Space: Physical facilities dedicated to the conduct of cancer focused research, and to the Center’s Shared Resources, and administration, are appropriate and adequate for the task.
  • Organizational Capabilities: The Center takes maximum advantage of institutional capabilities in cancer research, engaging in appropriate planning and evaluation of Center strategies and activities. If a consortium is proposed, the consortium institution(s) add significant cancer research expertise to the Center.
  • Transdisciplinary Collaboration and Coordination: Substantial coordination, interaction, and collaboration, both among Center members from a variety of disciplines and between Center members and investigators in other institutions, enhance and add value to the productivity and quality of research. As appropriate to the nature of the research, Centers facilitate transition of scientific findings through the translational continuum, via coordination of research across NCI and other funding mechanisms and through collaborations with other partners.
  • Cancer Focus: The structure and objectives of the Center’s Research Programs and other components, as well as, the Center members’ grants, contracts, publications, demonstrate a clearly defined cancer research focus.
  • Institutional Commitment: The Center is a formal organizational component of the institution, with sufficient space, positions, and discretionary resources to ensure its stability and fulfill the Center’s objectives. The Center Director has authorities appropriate for managing the Center and furthering its scientific mission. The institution recognizes team science in its promotion and tenure policies.
  • Center Director: The Director is a highly qualified scientist and administrator with leadership experience and expertise appropriate for establishing a vision for the Center, advancing scientific goals, and managing a complex organization. She or he is effective in using institutionally designated authorities to manage the Center.

Funding Information

Budget should not exceed $1.2 million (Basic Cancer Center), $1.4 million (Clinical Cancer Center), $1.5 million (Comprehensive Cancer Center) in direct costs per year for the project period.

Project Period

5 years

Eligibility Criteria

Higher Education Institutions – Includes all types

  • Public/State Controlled Institutions of Higher Education
  • Private Institutions of Higher Education

Nonprofits Other Than Institutions of Higher Education

  • Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
  • Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)

For-Profit Organizations

  • Small Businesses
  • For-Profit Organizations (Other than Small Businesses)

Local Governments

  • State Governments
  • County Governments
  • City or Township Governments
  • Special District Governments
  • Indian/Native American Tribal Governments (Federally Recognized)
  • Indian/Native American Tribal Governments (Other than Federally Recognized)

Federal Governments

  • Eligible Agencies of the Federal Government
  • U.S. Territory or Possession

Other

  • Independent School Districts
  • Public Housing Authorities/Indian Housing Authorities
  • Native American Tribal Organizations (other than Federally recognized tribal governments)
  • Faith-based or Community-based Organizations
  • Regional Organizations

For more information, visit Grants.gov.

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