The National Institutes of Health (NIH) NIDDK Catalyst Award is designed to complement NIDDK’s traditional, investigator-initiated grant programs by supporting individual scientists who propose pioneering and transformational studies in topic areas of interest to NIDDK’s Division of Diabetes, Endocrinology and Metabolic Diseases, and to NIDDK’s Division of Digestive Diseases and Nutrition.
Donor Name: National Institutes of Health (NIH)
State: All States
County: All Counties
U.S. Territory: American Samoa, Guam, Commonwealth of Puerto Rico, Commonwealth of Northern Mariana Islands, U.S. Virgin Islands
Type of Grant: Award
Deadline: 09/28/2023
Size of the Grant: $500,000
Grant Duration: 5 years
Details:
Applications should be focused on major scientific challenges and have the potential to produce an unusually high impact on diseases and conditions that are central to the mission of these two divisions within NIDDK. To be considered responsive to this initiative, the proposed research should reflect new and novel scientific directions that are distinct from concepts and approaches being pursued in the investigator’s research program or elsewhere.
Applications submitted to this NOFO should be directly focused on diseases or conditions that are central to the mission of either the Division of Diabetes, Endocrinology and Metabolic Diseases (DEMD), or the Division of Digestive Diseases and Nutrition (DDN) of the NIDDK. Research focused on diseases or conditions central to the mission of NIDDK’s Division of Kidney, Urologic and Hematologic Diseases will not be considered responsive to this initiative.
Research areas of interest for DEMD include:
- Diabetes
- diabetes and other metabolic disorders, including inborn errors of metabolism and rare genetic metabolic diseases such as lipodystrophy and maturity onset diabetes of the young (MODY); non-pulmonary aspects of cystic fibrosis pathogenesis and pathophysiology; metabolic or endocrine complications related to HIV or anti-retroviral therapy; complications of diabetes that affect multiple organ systems, or the specific complications of diabetic foot ulcers, peripheral sensory neuropathy, and neurovascular or neurocognitive complications of diabetes.
- Endocrinology
- development, metabolism and basic biology of the endocrine system including pathophysiology of endocrine disorders involving thyroid and parathyroid; neuroendocrinology of energy balance, including neural pathways and peptides that regulate feeding behavior, satiety, and energy expenditure.
- Metabolism
- mechanisms regulating metabolism, metabolic dysfunction, and tissue crosstalk in specific peripheral tissues such as adipose, bone, muscle, or liver; effects of the intrauterine environment on metabolic responses in offspring.
Research areas of interest for DDN include:
- Digestive Diseases: achalasia, gastroesophageal reflux disease, peptic ulcer disease, gastrointestinal bleeding, diarrhea, malabsorption, appendicitis, inflammatory bowel diseases, celiac disease, functional GI and motility disorders, metaplasia, and dysplasia;
- Hepatobiliary diseases: nonalcoholic fatty liver disease, chronic hepatitis, cirrhosis, drug-induced liver injury, autoimmune liver diseases [autoimmune hepatitis, sclerosing cholangitis, primary biliary cholangitis], biliary atresia and cholestatic liver diseases of childhood, genetic liver diseases, gallbladder disease, liver transplantation; as well as investigation of molecular pathways involved in liver development, injury, inflammation, repair, cholestasis, and fibrosis;
- Exocrine pancreatic diseases: acute and chronic pancreatitis, autoimmune pancreatitis (idiopathic and familial), pancreatogenic diabetes;
- Pathophysiological mechanisms related to obesity and nutrition including nutrient metabolism and energy balance, gut-brain interactions related to food intake, integration of microbiome-nutrient host interactions, and integrated response to a meal;
- Mechanisms of central and peripheral neural control of the normal digestive system and the role of neural mechanisms in diseases and conditions;
- HIV/AIDS research in the context of the above areas of interest.
Funding Information
Application budgets are limited to $500,000 direct costs per year.
Project Period
The maximum project period is 5 years.
Eligibility Criteria
Higher Education Institutions
- Public/State Controlled Institutions of Higher Education
- Private Institutions of Higher Education
The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:
- Hispanic-serving Institutions
- Historically Black Colleges and Universities (HBCUs)
- Tribally Controlled Colleges and Universities (TCCUs)
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
Nonprofits Other Than Institutions of Higher Education
- Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
For-Profit Organizations
- Small Businesses
- For-Profit Organizations (Other than Small Businesses)
Local Governments
- State Governments
- County Governments
- City or Township Governments
- Special District Governments
- Indian/Native American Tribal Governments (Federally Recognized)
- Indian/Native American Tribal Governments (Other than Federally Recognized)
Federal Governments
- Eligible Agencies of the Federal Government
- U.S. Territory or Possession
Other
- Independent School Districts
- Public Housing Authorities/Indian Housing Authorities
- Native American Tribal Organizations (other than Federally recognized tribal governments)
- Faith-based or Community-based Organizations
- Regional Organizations
For more information, visit Grants.gov.
