The purpose of The Interventions that Address Structural Racism to Reduce Kidney Health Disparities Funding Opportunity Announcement (FOA) is to support a Research Coordinating Center (RCC) that will work collaboratively with Intervention Sites in a Consortium to develop and test meaningful interventions that aim to dismantle or mitigate the effects of structural racism to reduce kidney health disparities.
Donor Name: National Institutes of Health
State: All States
County: All Counties
Territory: American Samoa, Commonwealth of Puerto Rico, Commonwealth of the Northern Mariana Islands, Guam, and U.S. Virgin Islands
Type of Grant: Grant
Deadline: 12/12/2022
Size of the Grant: $500,000
Grant Duration: 5 years
Details:
This Funding Opportunity Announcement (FOA) invites applications for the Research Coordinating Center (RCC) that will lead, manage, and harmonize efforts for the Consortium. The specific activities of the RCC will include: 1) providing organization, management, and administrative support of Consortium activities; 2) providing research coordination, data management and data analyses for Consortium studies; and 3) fostering research collaborations and helping to build a community of investigators with skills to develop, implement, and disseminate effective, scalable, and sustainable interventions that address the structural drivers of kidney health disparities.
Scope of Activities for Research Coordinating Center
- The Interventions that Address Structural Racism to Reduce Kidney Health Disparities FOA invites applications for a Research Coordinating Center (RCC) that will work collaboratively with Intervention Sites in a Consortium. The Consortium will support community-engaged clinical trials to test novel interventions that dismantle or mitigate the effects of structural determinants that perpetuate inequities in the care and outcomes of people living with kidney disease. Studies proposed by the successful applicants may be substantially revised by the Steering Committee prior to being undertaken by the Consortium, including the potential of harmonizing intervention components and data collection measures across Intervention Sites. The final interventions undertaken by the Consortium may include none, some, or all the interventions proposed by grant applicants. The Consortium also will help to foster collaborations between investigators with expertise in kidney health disparities and health equity research and patients, community members, community-based organizations, and other key stakeholders.
- This FOA is intended to support one RCC to facilitate collaboration and communication between Intervention Sites supported under the companion RFA [RFA-DK-22-014].The specific activities of the RCC will include, but are not limited to:
- Organization and Management
- Providing leadership for the administrative and research coordination functions for the Consortium.
- Establishing and implementing an evaluation plan for the achievement of Consortium goals.
- Providing logistical project management support, including developing a coordinating structure, organizing meetings (e.g., steering committee, executive committee, and sub-committee meetings), maintaining documentation, preparing reports and presentations for Consortium related meetings.
- Establishing and convening meetings with a community advisory board representing the population(s) addressed by the Consortium research project(s).
- Coordinating meetings with the NIDDK-appointed Data and Safety Monitoring Board (DSMB) and preparing reports and presentations.
- Facilitating collaboration, communication, and resource sharing between the RCC, study investigators, clinical and/or community sites/partners, and NIH Program Staff, including maintaining a Consortium directory and a web-based platform to facilitate information sharing.
- Ensuring and facilitating routine report back of study progress and findings to community partners.
- Supporting sharing and exchange of best practices for community engagement, recruitment approaches, and engagement and retention of participants.
- Coordinating dissemination of study findings and tracking manuscript proposals and publications resulting from Consortium efforts.
- Developing and coordinating the review and approval of ancillary studies that leverage the research infrastructure of the Consortium.
- Create and administer an Opportunity Pool of funds to address gaps or form new partnerships.
- Research Coordination, Data Management, Data Sharing, and Data Analyses
- Leading the Consortium in collaborative efforts to develop and refine the final study design(s) and protocol(s) for Consortium project(s), including the potential of developing a unifying study across all Intervention Sites, implementing a common intervention component at each Intervention Site, or coordinating different projects at each Intervention Site.
- Working with the Intervention Sites to identify or develop common data elements, data standards, and common data collection processes to be implemented across Intervention Sites.
- Providing overall data management, including establishing a central data base, coordinating data harmonization and data sharing across all project sites (where not otherwise prohibited such as by Tribal sovereignty), tracking study progress, and providing biostatistical, data management, and trial design and analytic expertise for Consortium-wide data analyses. This effort also includes preparing the final curated data transfer to the NIDDK Central Repository.
- Developing and maintaining an updated Consortium Manual of Procedures (MOPs) for project activities.
- Training staff on study protocols.
- Providing clinical study and site monitoring and quality control of data collected for Consortium projects.
- Tracking and facilitating approval from IRBs at the Intervention Sites, including issues related to data sharing ((where not otherwise prohibited such as by Tribal sovereignty).
- Monitoring the community engagement activities at Intervention Sites and ensuring activities foster strong and sustainable relationships with community partners.
- Negotiating material transfer agreements and data use agreements between institutions involved in the Consortium.
- Foster Research Collaborations and Community Engagement
- Coordinating collaborative opportunities to help build a community of investigators and community-based organizations equipped with essential skills to develop, implement and disseminate effective, scalable, and sustainable interventions that address structural racism to reduce kidney health disparities.
- Facilitating sharing of strategies and lessons learned from Consortium studies.
- Organization and Management
Funding Information
- The direct costs for the Research Coordinating Center U24 award are expected to be $500,000 direct costs per year (excluding Opportunity Pool). Applicants may ask for $100,000 or more per year for the Opportunity Pool. All Opportunity Pool costs are inclusive of any F&A for the Research Coordinating Center and the subawardees.
- The maximum project period is 5 years.
Eligibility Criteria
- Higher Education Institutions
- Public/State Controlled Institutions of Higher Education
- Private Institutions of Higher Education
- The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:
- Nonprofits Other Than Institutions of Higher Education
- Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- For-Profit Organizations
- Small Businesses
- For-Profit Organizations (Other than Small Businesses)
- Local Governments
- State Governments
- County Governments
- City or Township Governments
- Special District Governments
- Indian/Native American Tribal Governments (Federally Recognized)
- Indian/Native American Tribal Governments (Other than Federally Recognized)
- Federal Governments
- Eligible Agencies of the Federal Government
- U.S. Territory or Possession
- Other
- Independent School Districts
- Public Housing Authorities/Indian Housing Authorities
- Native American Tribal Organizations (other than Federally recognized tribal governments)
- Faith-based or Community-based Organizations
- Regional Organizations.
For more information, visit Grants.gov.
