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Leveraging Network Infrastructure to Advance Research for Women, Children, Pregnant and Lactating Individuals, and Persons with Disabilities

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The National Institutes of Health (NIH) is seeking applications for multisite clinical trials and large scale observational studies developed in conjunction with NICHD Networks that will be conducted using NICHD-supported Network infrastructure.

Donor Name: National Institutes of Health (NIH)

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States: All States

County: All Counties

U.S. Territories: American Samoa, Guam, the Northern Mariana Islands, Puerto Rico, and the U.S. Virgin Islands

Type of Grant: Grant

Deadline: 06/07/2026

Grant Duration: 5 years

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Details:

The goal of this FOA is to operationalize the previously reported NICHD guiding principles for multisite clinical trials delineated in Notice NOT-HD-19-034.

  • Enhancing the rigor and reproducibility of clinical trial protocols
    • NICHD is committed to this trans-NIH goal, and will ensure that multisite clinical trial protocols are submitted through the peer review process and that NICHD staff members have the tools to provide oversight of milestone planning, progress review, and ongoing risk management. This effort will include the identification of methods to minimize staff exposure to real and perceived conflicts of interest, ensure stewardship of public funds, increase accountability, and maintain public trust.
  • Promoting greater availability of multisite clinical trial infrastructure to support trials from a wider range of investigators
    • Maximizing the availability of research resources facilitates open access and potentially enhances fair competition. NICHD invests in the training of well-qualified, clinically trained scientists with many innovative ideas. The institute will find ways to make vital infrastructure for multisite clinical trials more available to the research community to help secure its continued growth.
  • Facilitating data sharing and access to biospecimens to efficiently expand research capacity for all investigators
    • This effort will maximize NICHD’s infrastructure investment by promoting secondary analysis, reproducibility of results, and enhanced data/specimen aggregation and sharing. Incorporating FAIR principles and enhancing data harmonization will allow NICHD and the scientific community to capitalize on artificial intelligence and other enhanced analytic techniques. These principles are becoming the gold standard across NIH, and NICHD will incorporate them to better address the public health needs of its populations.
  • Facilitating greater involvement of diverse populations in multisite clinical trials
    • Health disparities and inclusion in clinical trials are significant concerns for the populations and conditions that are priorities for NICHD. Infrastructure for multisite trials needs to reach racially and geographically diverse populations to advance our scientific mission.

Although the goal is to progressively include additional NICHD Networks, the initial NICHD Networks to be included in this initiative are:

  • Maternal-Fetal Medicine Units Network
  • Neonatal Research Network
  • Global Network for Women’s and Children’s Health Research
  • Collaborative Pediatric Critical Care Research Network
  • Pelvic Floor Disorders Network.

Award Project Period

The scope of the proposed project should determine the project period and may be up to 5 years.

Eligibility Information

Eligible Organizations

Higher Education Institutions

  • Public/State Controlled Institutions of Higher Education
  • Private Institutions of Higher Education

The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:

  • Hispanic-serving Institutions
  • Historically Black Colleges and Universities (HBCUs)
  • Tribally Controlled Colleges and Universities (TCCUs)
  • Alaska Native and Native Hawaiian Serving Institutions
  • Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)

Nonprofits Other Than Institutions of Higher Education

  • Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
  • Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)

Local Governments

  • State Governments
  • County Governments
  • City or Township Governments
  • Special District Governments
  • Indian/Native American Tribal Governments (Federally Recognized)
  • Indian/Native American Tribal Governments (Other than Federally Recognized)

Federal Government

  • Eligible Agencies of the Federal Government
  • U.S. Territory or Possession

Other

  • Independent School Districts
  • Public Housing Authorities/Indian Housing Authorities
  • Native American Tribal Organizations (other than Federally recognized tribal governments)
  • Faith-based or Community-based Organizations
  • Regional Organizations

Foreign Institutions

  • Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.
  • Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

For more information, visit Grants.gov.

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