The Centers for Disease Control and Prevention is seeking applications for ‘Implementing Pre-exposure Prophylaxis for HIV Prevention in Syringe Service Programs’.
Donor Name:Centers for Disease Control
Country: United States
State: All States
Type of Grant: Grant
Deadline (mm/dd/yyyy): 01/18/2022
Size of the Grant: $625,000
Grant Duration: 4 Years
Details:
The purpose of this Notice of Funding Opportunity (NOFO) is to support implementation research on combining HIV prevention modalities to add navigation for HIV pre-exposure prophylaxis (PrEP) at syringe service programs (SSPs) for people who inject drugs (PWID). The recipient should be an organization or institution that includes or partners with multiple and diverse SSPs. CDC is interested in increasing PrEP care through SSPs by incorporating more PrEP navigation and support into standard processes. The NOFO seeks effectiveness-implementation research on the acceptability and feasibility of a navigator-enhanced PWID PrEP service bundle at SSPs and optimizing it for initiation and retention in PrEP care among adult PWID. Applied research resulting from this funding is expected to strengthen combined HIV prevention for PWID and is aligned with the HIV National Strategic Plan (2021-2025) and the Ending the HIV Epidemic in the U.S. (EHE) initiative “Prevent” Pillar.
Objectives/Outcomes
This implementation study should address the following research gap and question: “How to design and deliver an enhanced PWID PrEP service bundle to increase initiation of, adherence to, and persistence of PrEP among PWID utilizing SSPs?”
Overall research objectives are to:
- Test the feasibility, acceptability, and effectiveness of implementing a PrEP intervention service bundle to increase uptake of and persistence with PrEP among PWID clients of SSPs.
- Assess barriers/facilitators to PrEP initiation among PWID at mobile and fixed care locations with SSPs. Tailor strategies to support PrEP initiation and persistence using peer navigators integrated into SSP workflow.
- Evaluate retention in PrEP care among PWID SSP clients over time.
- Assess costs of the peer enhanced PWID PrEP service bundle and compare with the cost of the existing PrEP referral or provision model.
Primary outcome: Percentage of study participants initiating PrEP before and after the introduction of a peer-enhanced PrEP navigation intervention for PWID.
Funding Information
- Estimated total funding available for the first year (first 12 months), including direct and indirect costs: $625,000
- Estimated total funding available for the entire project period of performance, including direct and indirect costs: $2,500,000
- Award Ceiling: $625,000 Per Budget Period
- Award Floor: $500,000 Per Budget Period
- Total Period of Performance Length: 4 year(s)
Target Population
The target population for this research is people who inject drugs (PWID) ≥18 years old, who report injection drug use in the past 12 months, use SSPs, are HIV-negative, and have indications for PrEP use based on injection drug use or sexual behavior criteria.
Applications should present a plan to enroll a sufficiently sized and diverse population of PWID who use SSPs, with representation by age, sex, and race/ethnicity reflective of the broader population of clients at the site.
Eligible Applicants
- Eligibility Category:
- State government
- County governments
- Special district governments
- City or township governments
- Independent school district
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher
- education)
- Nonprofits without 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Additional Eligibility Category: The following types of Higher Education Institutions are always encouraged to apply for CDC support as Public or Private Institutions of Higher Education:
- Governments:
- Eligible Agencies of the Federal Government
- U.S. Territory or Possession
- Other:
- Faith-based or Community-based Organizations
- Regional Organizations
For more information, visit Grants.gov.
